Products

LOXO-292/Selpercatinib
 
product description
Product: LOXO-292/Selpercatinib
CAS RN: 2152628-33-4
Molecular Formula:
Formula Weight:3 525.6
 
Physical Characters and Index
English name: LOXO-292
CAS number: 2152628-33-4
Molecular formula: C29H31N7O3
Molecular weight: 525.6
Density:1.36±0.1 g/cm3(Predicted)
 
Use and description
Secatinib is a potent Src inhibitor with IC50 of 2.7nM. It also effectively acts on c-Yes, Fyn, Lyn, Blk, Fgr and LcChemicalbookk; it has a slightly lower activity on Abl and EGFR (L858R and L861Q). Secatinib is the first inhibitor of the Src pathway in human tumor tissues.