Products

4-Aminobutyric acid
 
product description
Product: 4-Aminobutyric acid
CAS RN: 56-12-2
Molecular Formula:
Formula Weight:3 103.12
 
Physical Characters and Index
Product Name:4-Aminobutyric acid
Other name:Gamma-aminobutyric acid/GABA
CAS:56-12-2
Molecular Formula:C4H9NO2
Molecular Weight:103.12
Purity:99%
Appearance:White or off-white crystalline powder.
Melting point:195 °C (dec.) (lit.)
Boiling point:248.0±23.0 °C(Predicted)
Storage conditions:2-8°C
 
Use and description
γ-Aminobutyric acid is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although in chemical terms it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, by convention refers to the alpha amino acids, which GABA is not, nor is it considered to be incorporated into proteins. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition’s upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.