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1. NMN restores the composition and function of intestinal flora caused by radiation disorders

Through the detection and comparison of the intestinal flora of the mice in the IR group and the NMNIR group, it was found that the IR group mice increased the abundance of harmful intestinal flora, such as Lactobacillus dunovani and Faecalibacterium. But surprisingly, the mice in the NMNIR group changed the diversity of intestinal flora by supplementing NMN and increased the abundance of beneficial intestinal flora, such as AKK bacteria. Experiments have shown that NMN restores the composition and function of gut microbiota dysregulated by radiation.

2. NMN alleviates intestinal fibrosis induced by radiation

The level of aSMA (fibrosis marker) in mice exposed to radiation was significantly increased. After supplementing NMN, not only the level of aSMA marker decreased significantly, but also the inflammatory factor TGF-b that promotes intestinal fibrosis also decreased significantly, indicating that supplementing NMN Can alleviate intestinal fibrosis induced by radiation.

In the context of the prevalence of electronic products, radiation has an increasing impact on people's work and life, especially the long-term impact on intestinal flora. NMN has a strong protective effect on intestinal health. This effect is not only achieved by relying on a certain substance or a certain pathway, but by regulating the distribution structure of the flora to promote the stability of intestinal function from multiple angles and multiple directions, which is also the basis for the various functions of NMN. Benefits provide an important reference.